ORAL ADMINISTRATION OF EXOGENOUS LACTASE IN TABLETS FOR PATIENTS DIAGNOSED WITH LACTOSE INTOLERANCE DUE TO PRIMARY HYPOLACTASIA
نویسندگان
چکیده
منابع مشابه
Oral Administration of Exogenous Lactase in Tablets for Patients Diagnosed with Lactose Intolerance Due to Primary Hypolactasia.
Background Primary hypolactasia is a common condition where a reduced lactase activity in the intestinal mucosa is present. The presence of abdominal symptoms due to poor absorption of lactose, which are present in some cases, is a characteristic of lactose intolerance. Objective Evaluate the efficacy of a product containing exogenous lactase in tablet form compared to a reference product wit...
متن کاملEffects of Exogenous Lactase Administration on Hydrogen Breath Excretion and Intestinal Symptoms in Patients Presenting Lactose Malabsorption and Intolerance
OBJECTIVE To establish whether supplementation with a standard oral dose of Beta-Galactosidase affects hydrogen breath excretion in patients presenting with lactose malabsorption. METHODS Ninety-six consecutive patients positive to H2 Lactose Breath Test were enrolled. Mean peak H2 levels, the time to reach the peak H2, the time to reach the cut-off value of 20 ppm, the cumulative breath H2 e...
متن کاملGenetics of lactase persistence and lactose intolerance.
The enzyme lactase that is located in the villus enterocytes of the small intestine is responsible for digestion of lactose in milk. Lactase activity is high and vital during infancy, but in most mammals, including most humans, lactase activity declines after the weaning phase. In other healthy humans, lactase activity persists at a high level throughout adult life, enabling them to digest lact...
متن کاملHypolactasia & lactose intolerance among three ethnic groups in Malaysia.
BACKGROUND & OBJECTIVES Prevalence of adult-type hypolactasia is known to vary among different countries and in different ethnic populations in the same country. The present study was undertaken to evaluate the prevalence of hypolactasia and lactose intolerance in three different ethnic populations living in similar environmental conditions in Malaysia. The correlation between different symptom...
متن کاملHypolactasia as a molecular basis of lactose intolerance.
Lactase-phlorizin hydrolase (LPH), a membrane-bound glycoprotein present in the luminal surface of enterocytes in the intestine is responsible for lactose intolerance, a phenomenon prevalent in humans worldwide. In the rodent intestine, the post-natal development of the LPH follows a specific pattern, such that the enzyme levels are high in the peri-natal period, but declines considerably upon ...
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ژورنال
عنوان ژورنال: Arquivos de Gastroenterologia
سال: 2016
ISSN: 0004-2803
DOI: 10.1590/s0004-28032016000400004